exRNAdisease

Entry Detail

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General Information

Database ID: exR0433490 RNA Name: FLNA RNA Type: mRNA Chromosome: chrX Starnd: - Coordinate: Start Site(bp): 154348524 End Site(bp): 154374638 External Links: ENSG00000196924

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCA2 chr9 137007234 137028922 - ABHD17A chr19 1876810 1885547 - AC008403.1 chr19 48465837 48472431 + AC008982.1 chr19 38817471 38840178 - AC027644.4 chr7 66628958 66811189 + AC138969.1 chr16 16317444 16350590 + AC233992.2 chr8 144353228 144355609 - AC245033.1 chr15 82536788 82573194 - ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - ADAMTS1 chr21 26835755 26845409 - ADAMTS19 chr5 129460281 129738683 + ADAMTSL4 chr1 150549369 150560937 + ADCY3 chr2 24819169 24919839 - ADCY6 chr12 48766194 48789037 - ADGRE5 chr19 14380501 14408725 + ADIPOR1 chr1 202940826 202958572 - ADNP2 chr18 80109262 80147523 + AFDN chr6 167826922 167972023 + AFG3L2 chr18 12328944 12377227 - AFMID chr17 78187317 78207701 + AGO2 chr8 140520156 140635633 - AGPAT1 chr6 32168212 32178096 - AGRN chr1 1020120 1056118 + AIP chr11 67483026 67491103 + AK4 chr1 65147549 65232145 + AKT2 chr19 40230317 40285536 - AL807752.6 chr9 137031241 137040436 - ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC015961.2 chr18 37243776 37247506 + AC026362.1 chr12 122975320 122982907 + AC079781.5 chr7 97851688 97972985 - AD000090.1 chr19 35557956 35581954 + AL021707.2 chr22 38667585 38681847 - AL137127.1 chr1 19072110 19075511 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.