exRNAdisease

General Information

Database ID:

exR0433646

RNA Name:

FUS

RNA Type:

mRNA

Chromosome:

chr16

Starnd:

Coordinate:

Start Site(bp):

31180110

End Site(bp):

31194871

External Links:

Disease Information

Disease Name:	Pediatric TB meningitis
Disease Category:	Infections
MeSH ID:	D014390
Type:	Diseases Category/Infections
Alias:	Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Pediatric TB meningitis
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AAGAB	chr15	67200667	67255195	-
ACTN4	chr19	38647649	38731589	+
ADCY6	chr12	48766194	48789037	-
AC091167.2	chr15	90249556	90272208	+
AC007192.1	chr19	18153158	18178117	+
AHCY	chr20	34280268	34311802	-
AAMP	chr2	218264123	218270257	-
AC010422.3	chr19	12643831	12648397	-
ABRACL	chr6	139028745	139043302	+
ACTR2	chr2	65227753	65271253	+
AC093525.1	chr16	2513965	2527955	+
AFDN	chr6	167826922	167972023	+
AL365205.1	chr6	41780349	41790141	+
AEBP2	chr12	19404045	19720801	+
AC093525.2	chr16	2496032	2520218	+
ACTR5	chr20	38748460	38772520	+
ACTB	chr7	5527148	5563784	-
AL359736.1	chr13	23979700	24321031	+
AC005832.4	chr12	4604944	4662643	+
AKT1S1	chr19	49869033	49878459	-
AC092143.1	chr16	89919165	89936092	+
ALDH4A1	chr1	18871430	18902724	-
ADGRL2	chr1	81306160	81992436	+
AC004922.1	chr7	99325879	99394653	+
ALDOA	chr16	30064164	30070457	+
AGTRAP	chr1	11736084	11754802	+
AC008878.3	chr19	7382834	7470241	+
AC138811.2	chr16	18788063	18801519	-
ACTG1	chr17	81509971	81523847	-
AKR7A2	chr1	19303965	19312146	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-221-3p	chrX	45746180	45746202	-
hsa-miR-4508	chr15	23562107	23562123	-
hsa-miR-4521	chr17	8186948	8186969	+

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005726.3	chr17	28573117	28574243	+
AC020928.2	chr19	36773712	36775908	-
AC023509.1	chr12	53441741	53467528	+
AC079781.5	chr7	97851688	97972985	-
AC096992.2	chr3	136837338	136839021	-
AC245014.3	chr1	145281116	145281462	+
AD000090.1	chr19	35557956	35581954	+
AL022311.1	chr22	37876148	37895563	+
AL031282.2	chr1	1702736	1737688	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.