exRNAdisease

Entry Detail

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General Information

Database ID: exR0434096 RNA Name: GPI RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 34359480 End Site(bp): 34402413 External Links: ENSG00000105220

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASDHPPT chr11 106075501 106098699 + ABLIM1 chr10 114431113 114768061 - AC007040.2 chr2 70939318 70995336 - AC008764.4 chr19 16577642 16660115 - AC010132.3 chr7 42909273 42932174 - AC010323.1 chr19 8308283 8321379 - AC010422.3 chr19 12643831 12648397 - AC092073.1 chr19 34396315 34409364 + AC137834.1 chr12 57249609 57296484 - AC245033.1 chr15 82536788 82573194 - ACSS1 chr20 25006230 25058980 - ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1A chr10 102461881 102502712 - ACTR3 chr2 113890063 113962596 + ADAMTS1 chr21 26835755 26845409 - ADO chr10 62804720 62808479 + AHCY chr20 34280268 34311802 - AIP chr11 67483026 67491103 + AL138752.2 chr9 37588413 38068687 - ALDH7A1 chr5 126531200 126595362 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-7106-3p chr12 113159113 113159135 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010655.2 chr7 128455937 128469197 + AC010655.4 chr7 128455840 128493859 + AC016876.2 chr17 7581964 7584086 - AC026362.1 chr12 122975320 122982907 + AC091564.7 chr11 6610883 6616594 - AC104971.3 chr18 58659858 58660524 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL096870.2 chr14 24209646 24215987 - AL136419.1 chr14 23969931 24051377 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.