exRNAdisease

Entry Detail

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General Information

Database ID: exR0434592 RNA Name: HLA-DPA1 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 33064569 End Site(bp): 33080775 External Links: ENSG00000231389

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD14B chr3 51968510 51983409 - ABLIM1 chr10 114431113 114768061 - AC004922.1 chr7 99325879 99394653 + AC005258.1 chr19 2269525 2341172 + AC006064.6 chr12 6556886 6607367 - AC008982.1 chr19 38817471 38840178 - AC010547.4 chr16 71447600 71489311 - AC020915.5 chr19 58228914 58315183 + AC026464.4 chr16 69299682 69322700 + AC138811.2 chr16 18788063 18801519 - ACADM chr1 75724347 75787575 + ACAP1 chr17 7336529 7351477 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADAR chr1 154582057 154628013 - ADIPOR1 chr1 202940826 202958572 - ADK chr10 74151202 74709963 + ADSL chr22 40346500 40390463 + AGPAT5 chr8 6708642 6761503 + AHCY chr20 34280268 34311802 - AK2 chr1 33007940 33080996 - AKT2 chr19 40230317 40285536 - AL022238.4 chr22 40346529 40410054 + AL136295.1 chr14 24189157 24213473 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007283.1 chr2 201166965 201167546 + AC140125.2 chr5 177782197 177794396 + AL096870.2 chr14 24209646 24215987 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.