exRNAdisease

Entry Detail

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General Information

Database ID: exR0434650 RNA Name: HNRNPF RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 43385617 End Site(bp): 43409166 External Links: ENSG00000169813

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARSD1 chr17 42950526 42964498 - ABCF2 chr7 151207837 151227166 - AC007192.1 chr19 18153158 18178117 + AC138811.2 chr16 18788063 18801519 - ACTG1 chr17 81509971 81523847 - ACTN1 chr14 68874143 68979440 - ADD3 chr10 109996368 110135565 + ADNP2 chr18 80109262 80147523 + ADSL chr22 40346500 40390463 + AGO4 chr1 35808016 35857890 + AGPAT5 chr8 6708642 6761503 + AHCY chr20 34280268 34311802 - AKAP12 chr6 151239967 151358559 + AL022238.4 chr22 40346529 40410054 + AL136295.1 chr14 24189157 24213473 - AL136295.4 chr14 24180395 24190416 - ALDH3A2 chr17 19648136 19685760 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC016026.1 chr22 17787652 17811497 - AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.