exRNAdisease

Entry Detail

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General Information

Database ID: exR0434651 RNA Name: HNRNPH1 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 179614178 End Site(bp): 179634784 External Links: ENSG00000169045

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand A4GALT chr22 42692121 42721298 - ABHD17A chr19 1876810 1885547 - AC004922.1 chr7 99325879 99394653 + AC008982.1 chr19 38817471 38840178 - AC068580.4 chr11 1734821 1763954 - AC068946.1 chr2 219075329 219170827 - AC073508.2 chr17 40627356 40665141 - AC091167.2 chr15 90249556 90272208 + AC097637.1 chr3 52221081 52231190 - ACER3 chr11 76860867 77026797 + ACKR3 chr2 236567787 236582354 + ACSL1 chr4 184755595 184826818 - ACSL3 chr2 222860942 222944639 + ACTG1 chr17 81509971 81523847 - ACTN4 chr19 38647649 38731589 + ADCK1 chr14 77800109 77935014 + ADHFE1 chr8 66432492 66468907 + ADIPOR1 chr1 202940826 202958572 - AEN chr15 88621337 88632281 + AHCY chr20 34280268 34311802 - AL021546.1 chr12 120438198 120460006 + ALDH4A1 chr1 18871430 18902724 - ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-150-5p chr19 49500832 49500853 - hsa-miR-532-3p chrX 50003204 50003225 + hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC009118.2 chr16 58392153 58392807 - AC016876.2 chr17 7581964 7584086 - AC024940.6 chr12 31280422 31280895 - AC245014.3 chr1 145281116 145281462 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.