exRNAdisease

Entry Detail

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General Information

Database ID: exR0434660 RNA Name: HNRNPUL1 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 41262496 End Site(bp): 41307787 External Links: ENSG00000105323

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC4 chr13 95019835 95301475 - ABCF1 chr6 30571393 30597179 + ABHD2 chr15 89087459 89202355 + AC008763.3 chr19 7678501 7682854 + AC024592.3 chr19 5866171 5903787 - AC026954.2 chr17 7312661 7319174 - AC138811.2 chr16 18788063 18801519 - ACAT2 chr6 159762045 159779112 + ACTB chr7 5527148 5563784 - ADNP2 chr18 80109262 80147523 + AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AKR1A1 chr1 45550543 45570049 + AKT1S1 chr19 49869033 49878459 - AL031708.1 chr16 1632259 1686715 + AL358113.1 chr9 69035747 69255187 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-650 chr22 22822791 22822811 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-632 chr17 32350169 32350187 + hsa-miR-1247-5p chr14 101560362 101560383 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AD000090.1 chr19 35557956 35581954 + AL121992.1 chr1 15586136 15603626 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.