exRNAdisease

Entry Detail

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General Information

Database ID: exR0436281 RNA Name: MARCKS RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 113857345 End Site(bp): 113863475 External Links: ENSG00000277443

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABT1 chr6 26596953 26600739 + AC009133.6 chr16 29812261 29820092 + AC010422.3 chr19 12643831 12648397 - AC011448.1 chr19 19516227 19536076 + AC048338.1 chr12 122207779 122266423 - AC087289.3 chr17 75898645 75930129 - ACKR3 chr2 236567787 236582354 + ACOT7 chr1 6264269 6394391 - ADAM15 chr1 155050566 155062775 + ADAR chr1 154582057 154628013 - ADCY1 chr7 45574140 45723116 + ADD3 chr10 109996368 110135565 + ADGRA3 chr4 22345071 22516066 - ADGRL2 chr1 81306160 81992436 + ADPRHL1 chr13 113399610 113453524 - AGPAT5 chr8 6708642 6761503 + ALDH9A1 chr1 165662216 165698863 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-19a-3p chr13 91350939 91350961 + hsa-miR-146a-5p chr5 160485372 160485393 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010478.1 chr5 51372736 51383332 - AC016394.2 chr10 73252791 73254349 + AC090114.2 chr7 128524016 128531069 - AC112907.3 chr3 186781780 186784179 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.