exRNAdisease

Entry Detail

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General Information

Database ID: exR0436489 RNA Name: MFGE8 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 88898683 End Site(bp): 88913381 External Links: ENSG00000140545

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007040.2 chr2 70939318 70995336 - AC131160.1 chr3 183815568 183884889 - AC245033.1 chr15 82536788 82573194 - ACER3 chr11 76860867 77026797 + ACTN1 chr14 68874143 68979440 - ACVR1B chr12 51951699 51997078 + ADO chr10 62804720 62808479 + ADRA2C chr4 3766348 3768526 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AFG3L2 chr18 12328944 12377227 - AGBL5 chr2 27042364 27070622 + AGO4 chr1 35808016 35857890 + AGRN chr1 1020120 1056118 + AHCY chr20 34280268 34311802 - AL022238.4 chr22 40346529 40410054 + AL359922.1 chr9 21802636 22029594 + AL512785.2 chr1 162365407 162383531 + ALDH3A2 chr17 19648136 19685760 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC144652.1 chr7 155295918 155297541 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AF106564.1 chr8 24912165 24914717 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.