exRNAdisease

Entry Detail

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General Information

Database ID: exR0436858 RNA Name: MT-CO1 RNA Type: mRNA Chromosome: chrMT Starnd: + Coordinate: Start Site(bp): 5904 End Site(bp): 7445 External Links: ENSG00000198804

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABLIM1 chr10 114431113 114768061 - AC120057.2 chr17 7240427 7244635 - AKT2 chr19 40230317 40285536 - AL022238.4 chr22 40346529 40410054 + ADAM9 chr8 38996869 39105261 + AFAP1 chr4 7758714 7939926 - ADAR chr1 154582057 154628013 - AC126283.2 chr4 109713916 109801999 - ABHD4 chr14 22598237 22613215 + ACAT1 chr11 108116695 108147603 + ADSL chr22 40346500 40390463 + AFDN chr6 167826922 167972023 + AEBP1 chr7 44104345 44114562 + AC005258.1 chr19 2269525 2341172 + ALCAM chr3 105366909 105576900 + ACP1 chr2 264140 278283 + ADD3 chr10 109996368 110135565 + AARS2 chr6 44298731 44313347 - AC245033.1 chr15 82536788 82573194 - ADPGK chr15 72751369 72785846 - ABCB7 chrX 75051048 75156732 - AC023055.1 chr12 55757275 55827546 - ACTB chr7 5527148 5563784 - AC092073.1 chr19 34396315 34409364 + ABCF1 chr6 30571393 30597179 + AC011462.1 chr19 41350853 41425001 + ADIPOR2 chr12 1688574 1788674 + ABCA7 chr19 1039997 1065572 + AHCY chr20 34280268 34311802 - AC104109.3 chr5 134167170 134226071 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005618.1 chr5 141326210 141329357 + AC007952.4 chr17 19112000 19112636 - AC010201.2 chr12 89367807 89369301 + AC016876.2 chr17 7581964 7584086 - AC018362.2 chr15 42567031 42569994 - AC020978.7 chr16 68224713 68227734 + AC026464.2 chr16 69463844 69466264 + AC112484.1 chr3 128860620 128871540 - AC116407.1 chr17 32141226 32143135 - AC132192.2 chr11 9459556 9460702 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.