exRNAdisease

Entry Detail

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General Information

Database ID: exR0437457 RNA Name: NME2 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 51165435 End Site(bp): 51171747 External Links: ENSG00000243678

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAR2 chr20 36236459 36270918 + AASDHPPT chr11 106075501 106098699 + ABHD6 chr3 58237532 58295693 + AC004832.3 chr22 30409255 30428990 + AC005258.1 chr19 2269525 2341172 + AC006030.1 chr2 74211604 74363377 - AC010422.3 chr19 12643831 12648397 - AC104472.3 chr3 155763043 155854442 - AC120057.2 chr17 7240427 7244635 - AC131160.1 chr3 183815568 183884889 - AC139530.2 chr17 81703371 81720539 + ACACA chr17 37084992 37406836 - ACBD6 chr1 180269653 180502954 - ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACVR2B chr3 38453890 38493142 + ADAR chr1 154582057 154628013 - ADAT1 chr16 75596981 75623300 - ADGRG6 chr6 142301854 142446266 + AKAP1 chr17 57085092 57121346 + AKAP8L chr19 15380050 15419141 - AKAP9 chr7 91940867 92110673 + AKIRIN1 chr1 38991276 39006059 + AKR1A1 chr1 45550543 45570049 + AL133352.1 chr10 100505628 100529881 - AL513165.2 chr9 37512547 37592469 - AL590764.2 chrX 71103987 71111575 - ALDH2 chr12 111766887 111817532 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-206 chr6 52144401 52144422 + hsa-miR-302c-3p chr4 112648366 112648388 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004224.2 chr16 3458071 3515564 + AC020915.3 chr19 58257270 58278808 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.