exRNAdisease

Entry Detail

---



General Information

Database ID: exR0441289 RNA Name: SND1 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 127652194 End Site(bp): 128092609 External Links: ENSG00000197157

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA1 chr9 104781006 104928155 - ABCF2 chr7 151207837 151227166 - AC005943.1 chr19 1578339 1605445 - AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC020915.5 chr19 58228914 58315183 + AC073610.2 chr12 48903503 48957365 - AC092143.1 chr16 89919165 89936092 + AC124312.1 chr15 24955034 25000276 + AC245033.1 chr15 82536788 82573194 - ACTB chr7 5527148 5563784 - ACTR1B chr2 97655939 97664044 - ACTR2 chr2 65227753 65271253 + ADRM1 chr20 62302093 62308862 + ADSL chr22 40346500 40390463 + AGO1 chr1 35869808 35930532 + AGTRAP chr1 11736084 11754802 + AHCY chr20 34280268 34311802 - AL022238.4 chr22 40346529 40410054 + AL031708.1 chr16 1632259 1686715 + AL365205.1 chr6 41780349 41790141 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-302b-3p chr4 112648489 112648511 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL049795.2 chr1 32170733 32176568 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.