exRNAdisease

Entry Detail

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General Information

Database ID: exR0441394 RNA Name: SOX4 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 21593751 End Site(bp): 21598619 External Links: ENSG00000124766

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011005.1 chr7 129126518 129130793 + AC131160.1 chr3 183815568 183884889 - AC135050.2 chr16 31083439 31094956 - ACSF3 chr16 89088375 89164121 + ACTR1A chr10 102461881 102502712 - ADGRL1 chr19 14147743 14206187 - AEN chr15 88621337 88632281 + AFDN chr6 167826922 167972023 + AHCYL1 chr1 109984765 110023742 + AKAP9 chr7 91940867 92110673 + AKIRIN2 chr6 87674860 87702233 - AL162417.1 chr9 133098121 133163914 - ALDH16A1 chr19 49453225 49471050 + ALDH1B1 chr9 38392702 38398661 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-25-3p chr7 100093571 100093592 - hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-378a-3p chr5 149732867 149732888 + hsa-miR-422a chr15 63870989 63871010 - hsa-miR-92b-3p chr1 155195237 155195258 + hsa-miR-483-5p chr11 2134181 2134202 - hsa-miR-7704 chr2 176188843 176188861 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007637.1 chr12 109111218 109125594 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.