exRNAdisease

Entry Detail

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General Information

Database ID: exR0441584 RNA Name: SRRM2 RNA Type: mRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 2752626 End Site(bp): 2772538 External Links: ENSG00000167978

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA2 chr9 137007234 137028922 - ABCB8 chr7 151028422 151047782 + ABCG2 chr4 88090150 88231628 - ABI1 chr10 26746593 26861087 - ABT1 chr6 26596953 26600739 + AC010422.3 chr19 12643831 12648397 - AC046185.1 chr17 63702845 63752097 - AC092143.1 chr16 89919165 89936092 + AC093525.1 chr16 2513965 2527955 + AC104452.1 chr3 49416777 49429314 - AC107871.1 chr15 68184032 68229718 - AC120057.2 chr17 7240427 7244635 - AC138811.2 chr16 18788063 18801519 - ACTB chr7 5527148 5563784 - ACTN4 chr19 38647649 38731589 + ADAM10 chr15 58588809 58749791 - ADAM15 chr1 155050566 155062775 + ADGRE5 chr19 14380501 14408725 + ADGRL2 chr1 81306160 81992436 + ADRM1 chr20 62302093 62308862 + AGGF1 chr5 77029251 77065234 + AGPAT1 chr6 32168212 32178096 - AHNAK chr11 62433542 62556235 - AK4 chr1 65147549 65232145 + AKT2 chr19 40230317 40285536 - ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3648 chr21 8987026 8987046 + hsa-miR-7847-3p chr11 1880105 1880125 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005696.4 chr17 2720801 2723947 - AC007952.4 chr17 19112000 19112636 - AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC026362.1 chr12 122975320 122982907 + AC051619.7 chr15 45200325 45200632 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.