exRNAdisease

Entry Detail

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General Information

Database ID: exR0441723 RNA Name: STMN1 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 25884181 End Site(bp): 25906991 External Links: ENSG00000117632

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABCE1 chr4 145098288 145129524 + ABHD16A chr6 31686955 31703356 - ABI2 chr2 203328239 203447728 + AC007192.1 chr19 18153158 18178117 + AC118549.1 chr1 77562416 77683419 - AC138811.2 chr16 18788063 18801519 - ACOT9 chrX 23701055 23766475 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN4 chr19 38647649 38731589 + ACTR1B chr2 97655939 97664044 - ACTR5 chr20 38748460 38772520 + AD000671.1 chr19 35745678 35754519 + ADAM19 chr5 157395534 157575775 - ADK chr10 74151202 74709963 + AGPS chr2 177392757 177559299 + AL117348.2 chr1 225886696 225924278 - AL136295.1 chr14 24189157 24213473 - AL136295.4 chr14 24180395 24190416 - ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-194-5p chr11 64891404 64891425 - hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-3917 chr1 25906384 25906403 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005618.1 chr5 141326210 141329357 + AC006504.5 chr19 27793431 27984984 + AC023509.1 chr12 53441741 53467528 + AC106864.1 chr4 112693047 112706810 - AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.