exRNAdisease

Entry Detail

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General Information

Database ID: exR0442334 RNA Name: TKT RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 53224712 End Site(bp): 53256052 External Links: ENSG00000163931

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + AC104532.1 chr19 5904841 5914707 + AC245033.1 chr15 82536788 82573194 - AC124312.1 chr15 24955034 25000276 + AC008982.1 chr19 38817471 38840178 - ACTR1A chr10 102461881 102502712 - ALDOA chr16 30064164 30070457 + ACO2 chr22 41469117 41528989 + ACAP1 chr17 7336529 7351477 + ABCA2 chr9 137007234 137028922 - AC104109.3 chr5 134167170 134226071 - ACLY chr17 41866917 41930542 - AC004922.1 chr7 99325879 99394653 + AC068580.4 chr11 1734821 1763954 - AL136454.1 chr1 192716132 192716653 + AD000671.2 chr19 35739252 35745432 - AGO4 chr1 35808016 35857890 + AC138969.1 chr16 16317444 16350590 + ACTB chr7 5527148 5563784 - AC007192.1 chr19 18153158 18178117 + ADAR chr1 154582057 154628013 - ACTG1 chr17 81509971 81523847 - AKT1 chr14 104769349 104795751 - AC010615.4 chr19 21405159 21491266 + AC018523.2 chr11 14493783 14520344 - AC004832.3 chr22 30409255 30428990 + ADSL chr22 40346500 40390463 + AKAP12 chr6 151239967 151358559 + AL022238.4 chr22 40346529 40410054 + ADRM1 chr20 62302093 62308862 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012236.1 chr15 31221999 31230838 - AC087521.3 chr11 43921059 44001157 + AC091564.7 chr11 6610883 6616594 - AC091729.3 chr7 1160374 1165607 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL031282.2 chr1 1702736 1737688 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.