exRNAdisease

Entry Detail

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General Information

Database ID: exR0442384 RNA Name: TMBIM6 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 49707725 End Site(bp): 49764934 External Links: ENSG00000139644

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKAP12 chr6 151239967 151358559 + AGA chr4 177430774 177442437 - ACTB chr7 5527148 5563784 - AATF chr17 36948954 37056871 + ACBD5 chr10 27195214 27242130 - ADAMTS1 chr21 26835755 26845409 - AL353588.1 chr6 44273194 44378957 + AC092647.5 chr7 55887277 55955239 + AC026464.4 chr16 69299682 69322700 + AGO2 chr8 140520156 140635633 - ABCG2 chr4 88090150 88231628 - AFF1 chr4 86935002 87141054 + AC004997.1 chr22 30285238 30299482 - AL139353.1 chr14 31334312 31457441 - AC048338.1 chr12 122207779 122266423 - AIF1L chr9 131096476 131123152 + AC078927.1 chr12 66123917 66169985 - ACSF2 chr17 50426158 50474845 + ADAM22 chr7 87934143 88202889 + ABHD8 chr19 17292131 17310236 - ALDOA chr16 30064164 30070457 + ACTG1 chr17 81509971 81523847 - AHCY chr20 34280268 34311802 - ACO2 chr22 41469117 41528989 + AC010422.3 chr19 12643831 12648397 - AASDHPPT chr11 106075501 106098699 + ACTL6A chr3 179562886 179588407 + AL162417.1 chr9 133098121 133163914 - AHNAK chr11 62433542 62556235 - ADRM1 chr20 62302093 62308862 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009446.1 chr8 71675300 71702786 + AC012360.3 chr2 105334027 105337475 - AC018521.1 chr17 47945424 47981736 + AC020978.7 chr16 68224713 68227734 + AC022140.1 chr5 25404733 25445925 - AC023509.1 chr12 53441741 53467528 + AD000090.1 chr19 35557956 35581954 + AF129075.2 chr21 29058073 29060095 - AL021707.3 chr22 38734730 38738990 + AL049543.1 chr6 28587378 28591747 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.