exRNAdisease

Entry Detail

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General Information

Database ID: exR0442873 RNA Name: TRIM28 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 58544064 End Site(bp): 58550722 External Links: ENSG00000130726

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD14A-ACY1 chr3 51974706 51989183 + AC005258.1 chr19 2269525 2341172 + AC007192.1 chr19 18153158 18178117 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC092647.5 chr7 55887277 55955239 + AC118553.2 chr1 99970011 100083321 + AC129492.3 chr17 8150816 8162975 - AC138811.2 chr16 18788063 18801519 - AC245033.1 chr15 82536788 82573194 - ACBD6 chr1 180269653 180502954 - ACLY chr17 41866917 41930542 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1A chr10 102461881 102502712 - ACTR3C chr7 150243916 150323725 - ACY1 chr3 51983340 51989197 + ADAM10 chr15 58588809 58749791 - ADAR chr1 154582057 154628013 - ADD1 chr4 2843857 2930076 + ADSL chr22 40346500 40390463 + AHCY chr20 34280268 34311802 - AHDC1 chr1 27534035 27604431 - AIDA chr1 222668013 222713210 - AK2 chr1 33007940 33080996 - AKAP12 chr6 151239967 151358559 + AKR1A1 chr1 45550543 45570049 + AL121758.1 chr20 646626 675800 - AL136295.5 chr14 24147548 24166452 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6807-5p chr19 58550285 58550306 + hsa-miR-6807-3p chr19 58550354 58550376 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC060780.1 chr17 43148368 43171037 - AC069281.2 chr7 100572232 100578700 - AC109460.3 chr16 28974804 28990775 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL117378.1 chr6 131901963 131920565 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.