exRNAdisease

Entry Detail

General Information

Database ID:

exR0443160

RNA Name:

TXNL1

RNA Type:

mRNA

Chromosome:

chr18

Starnd:

-

Coordinate:

Start Site(bp):

56597209

End Site(bp):

56651600

External Links:

ENSG00000091164

Disease Information

Disease Name:	Pediatric TB meningitis
Disease Category:	Infections
MeSH ID:	D014390
Type:	Diseases Category/Infections
Alias:	Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Pediatric TB meningitis
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AAR2	chr20	36236459	36270918	+
AC005832.4	chr12	4604944	4662643	+
AC245033.1	chr15	82536788	82573194	-
ACSF3	chr16	89088375	89164121	+
AHNAK	chr11	62433542	62556235	-
AIMP1	chr4	106315544	106349456	+
AKIP1	chr11	8911139	8920084	+
AL136295.4	chr14	24180395	24190416	-

miRNA targets:

NA

circRNA targets:

NA

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC091564.7	chr11	6610883	6616594	-
AC245033.4	chr15	82533175	82540008	-

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.