exRNAdisease

Entry Detail

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General Information

Database ID: exR0443195 RNA Name: UBALD2 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 76265348 End Site(bp): 76271298 External Links: ENSG00000185262

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCA3 chr16 2275881 2340746 - AC005943.1 chr19 1578339 1605445 - AC008763.3 chr19 7678501 7682854 + AC010422.3 chr19 12643831 12648397 - AC011511.1 chr19 10305427 10316009 - AC024592.3 chr19 5866171 5903787 - AC092647.5 chr7 55887277 55955239 + AC093525.1 chr16 2513965 2527955 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADPRHL2 chr1 36088892 36093932 + AFF1 chr4 86935002 87141054 + AGER chr6 32180968 32184322 - AGO1 chr1 35869808 35930532 + AHCY chr20 34280268 34311802 - AKAP8L chr19 15380050 15419141 - AKNA chr9 114334156 114394405 - AL136531.2 chr20 1317571 1393096 - AL928654.3 chr14 105487199 105492267 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - AC067852.2 chr17 42552436 42554748 - AL021707.2 chr22 38667585 38681847 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.