exRNAdisease

Entry Detail

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General Information

Database ID: exR0443263 RNA Name: UBR4 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 19074510 End Site(bp): 19210266 External Links: ENSG00000127481

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + ABHD13 chr13 108218392 108234243 + ABI2 chr2 203328239 203447728 + ABL2 chr1 179099330 179229684 - AC093525.2 chr16 2496032 2520218 + AC138894.1 chr16 28456371 28492098 - ACD chr16 67657512 67660815 - ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - ADORA2A chr22 24417879 24442357 + AFG3L2 chr18 12328944 12377227 - AGAP3 chr7 151085831 151144436 + AGO2 chr8 140520156 140635633 - AHCY chr20 34280268 34311802 - AK7 chr14 96392128 96489427 + AKAP13 chr15 85380571 85749358 + AL138752.2 chr9 37588413 38068687 - AL139300.1 chr14 103562962 103685924 + AL357673.1 chr1 54132686 54200073 - AL513165.2 chr9 37512547 37592469 - ALCAM chr3 105366909 105576900 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3620-3p chr1 228097320 228097341 + hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand A1BG-AS1 chr19 58347718 58355455 + AC109460.3 chr16 28974804 28990775 + AD000090.1 chr19 35557956 35581954 + AL096870.2 chr14 24209646 24215987 - AL137127.1 chr1 19072110 19075511 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.