exRNAdisease

Entry Detail

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General Information

Database ID: exR0443474 RNA Name: VCP RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 35056064 End Site(bp): 35072627 External Links: ENSG00000165280

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + ABHD12 chr20 25294742 25390835 - AC005258.1 chr19 2269525 2341172 + AC010422.3 chr19 12643831 12648397 - AC073896.1 chr12 56285916 56316059 - AC091167.2 chr15 90249556 90272208 + AC093525.2 chr16 2496032 2520218 + ACADS chr12 120725774 120740008 + ACBD6 chr1 180269653 180502954 - ACTG1 chr17 81509971 81523847 - ADAR chr1 154582057 154628013 - ADH5 chr4 99070978 99088801 - AL121753.1 chr20 35267885 35280043 - ALDH2 chr12 111766887 111817532 + ALDH7A1 chr5 126531200 126595362 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-331-3p chr12 95308480 95308500 + hsa-miR-339-5p chr7 1022990 1023012 - hsa-miR-520a-5p chr19 53690895 53690915 + hsa-miR-450b-5p chrX 134540231 134540252 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002310.1 chr16 30534752 30537149 + AC112484.1 chr3 128860620 128871540 - AC132217.1 chr11 2129121 2129964 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL031282.2 chr1 1702736 1737688 - AL121992.1 chr1 15586136 15603626 - AL135925.1 chr10 79825902 79827602 + AL136985.3 chr1 58715609 58771295 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.