exRNAdisease

Entry Detail

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General Information

Database ID: exR0443749 RNA Name: XRCC5 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 216107464 End Site(bp): 216206303 External Links: ENSG00000079246

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + AC002985.1 chr19 18907013 18934397 - AC023055.1 chr12 55757275 55827546 - AC097637.1 chr3 52221081 52231190 - AC107871.1 chr15 68184032 68229718 - AC120057.2 chr17 7240427 7244635 - AC124312.1 chr15 24955034 25000276 + AC244197.3 chrX 149477104 149540926 - AC245033.1 chr15 82536788 82573194 - ACO1 chr9 32384603 32454769 + ACSS2 chr20 34872146 34927962 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR2 chr2 65227753 65271253 + ADA chr20 44619522 44652233 - ADGRA3 chr4 22345071 22516066 - ADIPOR2 chr12 1688574 1788674 + AFF1 chr4 86935002 87141054 + AHCY chr20 34280268 34311802 - AIF1L chr9 131096476 131123152 + AIMP1 chr4 106315544 106349456 + AKIRIN1 chr1 38991276 39006059 + AKR1A1 chr1 45550543 45570049 + AL136295.4 chr14 24180395 24190416 - AL162417.1 chr9 133098121 133163914 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC040162.3 chr16 67882461 67886367 + AC136475.2 chr11 310139 311141 - AC245033.4 chr15 82533175 82540008 - AFDN-DT chr6 167822103 167826812 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.