exRNAdisease

Entry Detail

---



General Information

Database ID: exR0443796 RNA Name: YWHAE RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 1344275 End Site(bp): 1400222 External Links: ENSG00000108953

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKR1B1 chr7 134442356 134459284 - ADO chr10 62804720 62808479 + ADAR chr1 154582057 154628013 - AC069368.1 chr15 64841883 64930920 + ACAT2 chr6 159762045 159779112 + AJUBA chr14 22971177 22982551 - AEN chr15 88621337 88632281 + ABCC1 chr16 15949577 16143074 + ACTG1 chr17 81509971 81523847 - AC104452.1 chr3 49416777 49429314 - AC015813.2 chr17 57989038 58007246 - ADH5 chr4 99070978 99088801 - ACADSB chr10 123008979 123058290 + AFDN chr6 167826922 167972023 + AJAP1 chr1 4654609 4792534 + ADM2 chr22 50481543 50486440 + ABRACL chr6 139028745 139043302 + ACTB chr7 5527148 5563784 - AKAP13 chr15 85380571 85749358 + AL590132.1 chr1 210858125 211134146 - ACLY chr17 41866917 41930542 - AHSA1 chr14 77457870 77469472 + ADCY2 chr5 7396138 7830081 + ALDOA chr16 30064164 30070457 + ALDH9A1 chr1 165662216 165698863 - AKAP9 chr7 91940867 92110673 + AGPAT1 chr6 32168212 32178096 - ACTR1A chr10 102461881 102502712 - AC092073.1 chr19 34396315 34409364 + AC010463.1 chr19 17267418 17282966 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7b-5p chr22 46113691 46113712 + hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008969.1 chr19 58002061 58011232 + AC010615.2 chr19 21444241 21463908 - AC020663.1 chr16 4730115 4752565 - AC026362.1 chr12 122975320 122982907 + AC040162.3 chr16 67882461 67886367 + AC106864.1 chr4 112693047 112706810 - AC125807.2 chr12 3041437 3044950 + AC132217.1 chr11 2129121 2129964 - AC139149.1 chr17 81514047 81527776 + AC145207.5 chr17 81878425 81881106 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL117378.1 chr6 131901963 131920565 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.