exRNAdisease

Entry Detail

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General Information

Database ID: exR0444151 RNA Name: ZNF354B RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 178859953 End Site(bp): 178888122 External Links: ENSG00000178338

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008982.1 chr19 38817471 38840178 - AC009690.3 chr15 72266746 72319946 - AC093668.1 chr7 102541501 102592444 - ACAD9 chr3 128879596 128916067 + ACLY chr17 41866917 41930542 - ACSF3 chr16 89088375 89164121 + ACTB chr7 5527148 5563784 - ACTR1A chr10 102461881 102502712 - ADAM15 chr1 155050566 155062775 + ADAM19 chr5 157395534 157575775 - ADARB1 chr21 45073853 45226560 + ADD2 chr2 70607618 70768225 - ADSL chr22 40346500 40390463 + AHCY chr20 34280268 34311802 - AHCYL1 chr1 109984765 110023742 + AIF1L chr9 131096476 131123152 + AKAP13 chr15 85380571 85749358 + AKT2 chr19 40230317 40285536 - AL021546.1 chr12 120438198 120460006 + AL022238.4 chr22 40346529 40410054 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4517 chr16 28958587 28958611 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC005899.4 chr17 32328441 32329395 + AC007952.4 chr17 19112000 19112636 - AC011445.1 chr19 39314651 39320858 - AC067930.1 chr8 143579636 143580670 + AC084082.1 chr8 66112667 66126632 + AC144548.1 chr12 110387463 110445548 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL117378.1 chr6 131901963 131920565 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.