Entry Detail


General Information

Database ID:exR0447068
RNA Name:CDKN1B
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):12715058End Site(bp):12722369
External Links:ENSG00000111276



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACACA
chr17
37084992
37406836
-
ACTB
chr7
5527148
5563784
-
ADAMTS18
chr16
77247813
77435034
-
ADAR
chr1
154582057
154628013
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-181a-5p
chr1
198859108
198859130
-
hsa-miR-181b-5p
chr9
124693725
124693747
+
hsa-miR-150-5p
chr19
49500832
49500853
-
hsa-miR-1323
chr19
53671978
53671999
+
hsa-miR-1185-5p
chr14
101044212
101044232
+
hsa-miR-1294
chr5
154347153
154347174
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC025287.1
chr16
75541399
75608445
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.