Entry Detail


General Information

Database ID:exR0448353
RNA Name:DKC1
RNA Type:mRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):154762742End Site(bp):154777689
External Links:ENSG00000130826



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTG1
chr17
81509971
81523847
-
ACTR1B
chr2
97655939
97664044
-
ADO
chr10
62804720
62808479
+
AFAP1
chr4
7758714
7939926
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-664a-5p
chr1
220200586
220200609
-
hsa-miR-664a-3p
chr1
220200549
220200571
-
hsa-miR-4312
chr15
68801860
68801878
-
hsa-miR-664b-5p
chrX
154768596
154768619
+
hsa-miR-664b-3p
chrX
154768635
154768656
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007996.1
chr18
26542971
26545791
-
AC073896.4
chr12
56162359
56190284
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.