exRNAdisease

Entry Detail

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General Information

Database ID: exR0450109 RNA Name: GNAS RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 58839718 End Site(bp): 58911192 External Links: ENSG00000087460

Disease Information

Disease Name: Disease Category: MeSH ID: Type: Alias:

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Ventricular Cerebrospinal Fluid Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AADAT chr4 170060222 170091699 - AL133352.1 chr10 100505628 100529881 - AC138811.2 chr16 18788063 18801519 - ACLY chr17 41866917 41930542 - AC004922.1 chr7 99325879 99394653 + ABRACL chr6 139028745 139043302 + AC012254.2 chr18 47108188 47176345 - AGFG1 chr2 227472152 227561214 + AKAP17A chrX 1591604 1602520 + AC005258.1 chr19 2269525 2341172 + ADCY2 chr5 7396138 7830081 + AIG1 chr6 143060496 143341058 + ADGRL2 chr1 81306160 81992436 + ACKR3 chr2 236567787 236582354 + ABI1 chr10 26746593 26861087 - ADA chr20 44619522 44652233 - AKT1 chr14 104769349 104795751 - ACTN4 chr19 38647649 38731589 + AGO3 chr1 35930718 36072500 + AC139530.2 chr17 81703371 81720539 + AC140504.1 chr16 15395754 15515348 + AC245033.1 chr15 82536788 82573194 - AHNAK chr11 62433542 62556235 - AC087289.3 chr17 75898645 75930129 - ADCY1 chr7 45574140 45723116 + ABHD17C chr15 80679684 80755621 + AL136531.2 chr20 1317571 1393096 - ALDH9A1 chr1 165662216 165698863 - AC092647.5 chr7 55887277 55955239 + AC010422.3 chr19 12643831 12648397 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-20a-5p chr13 91351072 91351094 + hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-146a-5p chr5 160485372 160485393 + hsa-miR-1181 chr19 10403505 10403525 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007637.1 chr12 109111218 109125594 + AC007952.4 chr17 19112000 19112636 - AC010442.1 chr5 466124 473098 - AC010642.2 chr19 58309727 58327248 - AC011447.3 chr19 20122569 20321305 - AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC040162.3 chr16 67882461 67886367 + AC090587.2 chr11 3854612 3855399 + AC106864.1 chr4 112693047 112706810 - AC124068.2 chr15 89335053 89336161 + AC132217.1 chr11 2129121 2129964 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.