Entry Detail


General Information

Database ID:exR0450730
RNA Name:HLA-E
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):30489509End Site(bp):30494194
External Links:ENSG00000204592



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASS
chr7
122073549
122144255
-
ABCA3
chr16
2275881
2340746
-
ABCB6
chr2
219209772
219218994
-
ABLIM1
chr10
114431113
114768061
-
AC007192.1
chr19
18153158
18178117
+
AC011448.1
chr19
19516227
19536076
+
AC097637.1
chr3
52221081
52231190
-
AC120057.2
chr17
7240427
7244635
-
ACTA2
chr10
88935074
88991339
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR8
chr3
53867066
53882152
-
ADCY3
chr2
24819169
24919839
-
ADPRHL2
chr1
36088892
36093932
+
AGFG2
chr7
100539203
100568220
+
AHCY
chr20
34280268
34311802
-
AL133352.1
chr10
100505628
100529881
-
AL136454.1
chr1
192716132
192716653
+
AL358113.1
chr9
69035747
69255187
+
AL928654.3
chr14
105487199
105492267
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3615
chr17
74748663
74748683
+
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC019205.1
chr6
73263212
73301789
+
AC026461.1
chr16
56682470
56687807
+
AC107926.1
chr17
20963722
20980238
+
AF274573.1
chrX
150915813
150920938
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.