Entry Detail


General Information

Database ID:exR0451942
RNA Name:LENG8
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):54448887End Site(bp):54462037
External Links:ENSG00000167615



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005670.2
chr17
46923133
47049932
+
ACTB
chr7
5527148
5563784
-
ACVR2B
chr3
38453890
38493142
+
ADCY6
chr12
48766194
48789037
-
AGO2
chr8
140520156
140635633
-
AGPAT5
chr8
6708642
6761503
+
AL136295.4
chr14
24180395
24190416
-
ALDH7A1
chr5
126531200
126595362
-
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-148a-3p
chr7
25949922
25949943
-
hsa-miR-130a-3p
chr11
57641252
57641273
+
hsa-miR-130b-3p
chr22
21653354
21653375
+
hsa-miR-148b-3p
chr12
54337278
54337299
+
hsa-miR-512-3p
chr19
53666729
53666750
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC011445.1
chr19
39314651
39320858
-
AC067930.1
chr8
143579636
143580670
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.