Entry Detail


General Information

Database ID:exR0452788
RNA Name:MKNK2
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):2037465End Site(bp):2051244
External Links:ENSG00000099875



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD1
chrX
153724856
153744755
+
ABCF2
chr7
151207837
151227166
-
ABHD17A
chr19
1876810
1885547
-
AC010422.3
chr19
12643831
12648397
-
AC010531.1
chr16
87302876
87334273
-
ACADVL
chr17
7217125
7225266
+
ACAT2
chr6
159762045
159779112
+
ACSL4
chrX
109624244
109733403
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADGRE5
chr19
14380501
14408725
+
ADPGK
chr15
72751369
72785846
-
AHCY
chr20
34280268
34311802
-
AIP
chr11
67483026
67491103
+
AK2
chr1
33007940
33080996
-
AK4
chr1
65147549
65232145
+
AL133352.1
chr10
100505628
100529881
-
AL590764.2
chrX
71103987
71111575
-
AL928654.3
chr14
105487199
105492267
+
ALDH2
chr12
111766887
111817532
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-1321
chrX
85835832
85835849
+
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008738.7
chr19
33207129
33207639
+
AC010997.3
chr10
75279726
75401246
-
AC016876.2
chr17
7581964
7584086
-
AC245884.11
chr19
54308915
54337168
-
AD000090.1
chr19
35557956
35581954
+
AL049796.1
chr1
93847174
93848939
+
AL138756.1
chr9
112028570
112039143
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.