exRNAdisease

Entry Detail

General Information

Database ID:

exR0456067

RNA Name:

RFX1

RNA Type:

mRNA

Chromosome:

chr19

Starnd:

-

Coordinate:

Start Site(bp):

13961530

End Site(bp):

14007039

External Links:

ENSG00000132005

Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Ventricular Cerebrospinal Fluid
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC068580.4	chr11	1734821	1763954	-
AC245033.1	chr15	82536788	82573194	-
ACVR1B	chr12	51951699	51997078	+
ADARB1	chr21	45073853	45226560	+
AIFM1	chrX	130129362	130165887	-

miRNA targets:

miRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
hsa-miR-19a-3p	chr13	91350939	91350961	+
hsa-miR-19b-3p	chr13	91351245	91351267	+
hsa-miR-32-5p	chr9	109046272	109046293	-
hsa-miR-296-5p	chr20	58817661	58817681	-
hsa-miR-367-3p	chr4	112647877	112647898	-
hsa-miR-491-5p	chr9	20716120	20716141	+
hsa-miR-671-5p	chr7	151238449	151238471	+

circRNA targets:

NA

lncRNA targets:

NA

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.