exRNAdisease

Entry Detail

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General Information

Database ID: exR0456784 RNA Name: SEC61A1 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 128051641 End Site(bp): 128071683 External Links: ENSG00000058262

Disease Information

Disease Name: Disease Category: MeSH ID: Type: Alias:

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Ventricular Cerebrospinal Fluid Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006064.6 chr12 6556886 6607367 - AC023055.1 chr12 55757275 55827546 - AC093525.2 chr16 2496032 2520218 + ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - ACTR3 chr2 113890063 113962596 + ADH5 chr4 99070978 99088801 - ADRM1 chr20 62302093 62308862 + AL139011.2 chr1 160216800 160285130 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-16-5p chr3 160404754 160404775 + hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-107 chr10 89592756 89592778 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-589-5p chr7 5495873 5495894 - hsa-miR-3136-3p chr3 69048966 69048987 - hsa-miR-4700-5p chr12 120723202 120723223 + hsa-miR-4700-3p chr12 120723233 120723258 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC020928.2 chr19 36773712 36775908 - AC023908.2 chr15 39770559 39801333 - AL049796.1 chr1 93847174 93848939 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.