exRNAdisease

Entry Detail

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General Information

Database ID: exR0457004 RNA Name: SH3PXD2A RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 103594027 End Site(bp): 103855543 External Links: ENSG00000107957

Disease Information

Disease Name: Disease Category: MeSH ID: Type: Alias:

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Ventricular Cerebrospinal Fluid Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007192.1 chr19 18153158 18178117 + ADK chr10 74151202 74709963 + AKAP8 chr19 15353385 15379798 - AL513165.2 chr9 37512547 37592469 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-25-3p chr7 100093571 100093592 - hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-363-3p chrX 134169382 134169403 - hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-448 chrX 114823524 114823545 + hsa-miR-92b-3p chr1 155195237 155195258 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-425-5p chr3 49020199 49020221 - hsa-miR-454-3p chr17 59137787 59137809 - hsa-miR-502-3p chrX 50014649 50014670 + hsa-miR-629-5p chr15 70079427 70079447 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.