Entry Detail


General Information

Database ID:exR0457042
RNA Name:SHMT2
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):57229573End Site(bp):57234935
External Links:ENSG00000182199



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABCG2
chr4
88090150
88231628
-
AC004922.1
chr7
99325879
99394653
+
AC010132.3
chr7
42909273
42932174
-
AC010422.3
chr19
12643831
12648397
-
AC138811.2
chr16
18788063
18801519
-
ACAT1
chr11
108116695
108147603
+
ACER3
chr11
76860867
77026797
+
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ACTR2
chr2
65227753
65271253
+
ADRM1
chr20
62302093
62308862
+
AGRN
chr1
1020120
1056118
+
AKAP12
chr6
151239967
151358559
+
AKNA
chr9
114334156
114394405
-
AL121594.1
chr14
35122549
35317474
+
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC091564.7
chr11
6610883
6616594
-
AC106864.1
chr4
112693047
112706810
-
AC132217.1
chr11
2129121
2129964
-
AC133644.3
chr2
87455476
87767359
+
AC137834.2
chr12
57229498
57230198
-
AC139149.1
chr17
81514047
81527776
+
AL136985.3
chr1
58715609
58771295
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.