Entry Detail


General Information

Database ID:exR0457431
RNA Name:SLC6A6
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):14402576End Site(bp):14489349
External Links:ENSG00000131389



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005258.1
chr19
2269525
2341172
+
ACOT7
chr1
6264269
6394391
-
AEBP2
chr12
19404045
19720801
+
AEN
chr15
88621337
88632281
+
AHCY
chr20
34280268
34311802
-
AKT1S1
chr19
49869033
49878459
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-140-5p
chr16
69933103
69933124
+
hsa-miR-149-5p
chr2
240456015
240456037
+
hsa-miR-491-5p
chr9
20716120
20716141
+
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-210-3p
chr11
568112
568133
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC067930.1
chr8
143579636
143580670
+
AC091564.7
chr11
6610883
6616594
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.