Entry Detail


General Information

Database ID:exR0457499
RNA Name:SMAD3
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):67063763End Site(bp):67195169
External Links:ENSG00000166949



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022384.1
chr3
10249372
10285796
+
ACP1
chr2
264140
278283
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-31-5p
chr9
21512158
21512178
-
hsa-miR-122-5p
chr18
58451088
58451109
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-663a
chr20
26208243
26208264
-
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-671-5p
chr7
151238449
151238471
+
hsa-miR-330-5p
chr19
45639049
45639070
-
hsa-miR-744-5p
chr17
12081909
12081930
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.