Entry Detail


General Information

Database ID:exR0457700
RNA Name:SORL1
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):121452314End Site(bp):121633763
External Links:ENSG00000137642



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC036214.3
chr8
79918860
80080775
-
ACTB
chr7
5527148
5563784
-
ACTC1
chr15
34790230
34795549
-
ACTR3
chr2
113890063
113962596
+
ADAR
chr1
154582057
154628013
-
AHCYL1
chr1
109984765
110023742
+
AHNAK
chr11
62433542
62556235
-
AJUBA
chr14
22971177
22982551
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
AL137058.2
chr13
52600042
52642542
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.