Entry Detail


General Information

Database ID:exR0457803
RNA Name:SPEN
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):15836095End Site(bp):15940456
External Links:ENSG00000065526



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD4
chr14
22598237
22613215
+
ABI2
chr2
203328239
203447728
+
ABR
chr17
1003518
1229738
-
ACIN1
chr14
23058564
23095614
-
ADAT3
chr19
1905399
1913447
+
ADCK2
chr7
140672945
140696261
+
AGAP3
chr7
151085831
151144436
+
AKR7A2
chr1
19303965
19312146
-
AKT2
chr19
40230317
40285536
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC011445.1
chr19
39314651
39320858
-
AC067930.1
chr8
143579636
143580670
+
AC100810.1
chr8
1761054
1764508
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.