Entry Detail


General Information

Database ID:exR0457820
RNA Name:SPINDOC
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):63813456End Site(bp):63827716
External Links:ENSG00000168005



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATK
chr17
81110487
81166221
-
AC010422.3
chr19
12643831
12648397
-
AC027796.3
chr17
3585149
3636249
-
ACAA2
chr18
49782164
49813953
-
ACTB
chr7
5527148
5563784
-
AL133352.1
chr10
100505628
100529881
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-541-3p
chr14
101064548
101064569
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.