Entry Detail


General Information

Database ID:exR0457865
RNA Name:SPTBN2
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):66685248End Site(bp):66729226
External Links:ENSG00000173898



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABLIM1
chr10
114431113
114768061
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
AKAP1
chr17
57085092
57121346
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-324-3p
chr17
7223308
7223330
-
hsa-miR-345-5p
chr14
100307876
100307897
+
hsa-miR-361-3p
chrX
85903641
85903663
-
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC021078.1
chr5
149494314
149504670
-
AC067930.1
chr8
143579636
143580670
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.