Entry Detail


General Information

Database ID:exR0457888
RNA Name:SREBF2
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):41833079End Site(bp):41907307
External Links:ENSG00000198911



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABCG2
chr4
88090150
88231628
-
AC005258.1
chr19
2269525
2341172
+
AC010422.3
chr19
12643831
12648397
-
AC015813.2
chr17
57989038
58007246
-
AC087289.3
chr17
75898645
75930129
-
AC118549.1
chr1
77562416
77683419
-
AC245033.1
chr15
82536788
82573194
-
ACLY
chr17
41866917
41930542
-
ACO2
chr22
41469117
41528989
+
ACSS3
chr12
80936414
81261210
+
ACTB
chr7
5527148
5563784
-
ACTN1
chr14
68874143
68979440
-
ADD2
chr2
70607618
70768225
-
ADGRG6
chr6
142301854
142446266
+
ADRM1
chr20
62302093
62308862
+
AFDN
chr6
167826922
167972023
+
AGO2
chr8
140520156
140635633
-
AKIRIN1
chr1
38991276
39006059
+
AKIRIN2
chr6
87674860
87702233
-
AL645941.2
chr6
32937364
32953122
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-33a-3p
chr22
41900989
41901010
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC026362.1
chr12
122975320
122982907
+
AC064807.1
chr8
51899268
51949874
+
AC078846.1
chr7
129604548
129611630
-
AC106864.1
chr4
112693047
112706810
-
AC132217.1
chr11
2129121
2129964
-
AC135048.1
chr16
30948386
30956511
+
AC138035.2
chr5
181329241
181342213
+
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.