Entry Detail


General Information

Database ID:exR0459465
RNA Name:TUB
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):8019244End Site(bp):8106112
External Links:ENSG00000166402



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABR
chr17
1003518
1229738
-
ADORA2A
chr22
24417879
24442357
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-19b-3p
chr13
91351245
91351267
+
hsa-miR-28-5p
chr3
188688794
188688815
+
hsa-miR-221-3p
chrX
45746180
45746202
-
hsa-miR-222-3p
chrX
45747036
45747056
-
hsa-miR-382-5p
chr14
101054316
101054337
+
hsa-miR-588
chr6
126484646
126484666
+
hsa-miR-129-2-3p
chr11
43581450
43581471
+
hsa-miR-708-5p
chr11
79402077
79402099
-
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.