Entry Detail


General Information

Database ID:exR0500034
RNA Name:GNAS
RNA Type:mRNA
Chromosome:chr20
Starnd:+
Coordinate:
Start Site(bp):58839718End Site(bp):58911192
External Links:ENSG00000087460



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AADAT
chr4
170060222
170091699
-
AL133352.1
chr10
100505628
100529881
-
AC138811.2
chr16
18788063
18801519
-
ACLY
chr17
41866917
41930542
-
AC004922.1
chr7
99325879
99394653
+
ABRACL
chr6
139028745
139043302
+
AC012254.2
chr18
47108188
47176345
-
AGFG1
chr2
227472152
227561214
+
AKAP17A
chrX
1591604
1602520
+
AC005258.1
chr19
2269525
2341172
+
ADCY2
chr5
7396138
7830081
+
AIG1
chr6
143060496
143341058
+
ADGRL2
chr1
81306160
81992436
+
ACKR3
chr2
236567787
236582354
+
ABI1
chr10
26746593
26861087
-
ADA
chr20
44619522
44652233
-
AKT1
chr14
104769349
104795751
-
ACTN4
chr19
38647649
38731589
+
AGO3
chr1
35930718
36072500
+
AC139530.2
chr17
81703371
81720539
+
AC140504.1
chr16
15395754
15515348
+
AC245033.1
chr15
82536788
82573194
-
AHNAK
chr11
62433542
62556235
-
AC087289.3
chr17
75898645
75930129
-
ADCY1
chr7
45574140
45723116
+
ABHD17C
chr15
80679684
80755621
+
AL136531.2
chr20
1317571
1393096
-
ALDH9A1
chr1
165662216
165698863
-
AC092647.5
chr7
55887277
55955239
+
AC010422.3
chr19
12643831
12648397
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-20a-5p
chr13
91351072
91351094
+
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-146a-5p
chr5
160485372
160485393
+
hsa-miR-1181
chr19
10403505
10403525
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007637.1
chr12
109111218
109125594
+
AC007952.4
chr17
19112000
19112636
-
AC010442.1
chr5
466124
473098
-
AC010642.2
chr19
58309727
58327248
-
AC011447.3
chr19
20122569
20321305
-
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC040162.3
chr16
67882461
67886367
+
AC090587.2
chr11
3854612
3855399
+
AC106864.1
chr4
112693047
112706810
-
AC124068.2
chr15
89335053
89336161
+
AC132217.1
chr11
2129121
2129964
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.