Entry Detail


General Information

Database ID:exR0500309
RNA Name:GSPT1
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):11868128End Site(bp):11916082
External Links:ENSG00000103342



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004922.1
chr7
99325879
99394653
+
AC010422.3
chr19
12643831
12648397
-
AC012184.2
chr16
70299194
70372582
+
AC023055.1
chr12
55757275
55827546
-
AC091167.2
chr15
90249556
90272208
+
AC245033.1
chr15
82536788
82573194
-
ACAA2
chr18
49782164
49813953
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AFG3L2
chr18
12328944
12377227
-
AIMP2
chr7
6009255
6023834
+
AKT2
chr19
40230317
40285536
-
ALDH16A1
chr19
49453225
49471050
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-621
chr13
40810826
40810846
+
hsa-miR-1181
chr19
10403505
10403525
-
hsa-miR-1248
chr3
186786675
186786701
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AC145285.6
chr16
28822431
28823969
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.