Entry Detail


General Information

Database ID:exR0500601
RNA Name:HMGA1
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):34236873End Site(bp):34246231
External Links:ENSG00000137309



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTR2
chr2
65227753
65271253
+
ADNP
chr20
50888916
50931437
-
AKR7A2
chr1
19303965
19312146
-
ADH5
chr4
99070978
99088801
-
ADM
chr11
10305073
10307397
+
AC008982.1
chr19
38817471
38840178
-
ADGRL1
chr19
14147743
14206187
-
AGPAT1
chr6
32168212
32178096
-
ADGRA3
chr4
22345071
22516066
-
AGFG2
chr7
100539203
100568220
+
ACLY
chr17
41866917
41930542
-
AJUBA
chr14
22971177
22982551
-
AK4
chr1
65147549
65232145
+
AAMP
chr2
218264123
218270257
-
AC009133.6
chr16
29812261
29820092
+
AHCYL2
chr7
129225023
129430211
+
AC068547.1
chr2
151802651
151973949
-
AC015813.2
chr17
57989038
58007246
-
AKAP13
chr15
85380571
85749358
+
AFTPH
chr2
64524305
64593005
+
AK5
chr1
77282019
77559966
+
ADRM1
chr20
62302093
62308862
+
ACER3
chr11
76860867
77026797
+
AL121594.1
chr14
35122549
35317474
+
ACTA1
chr1
229431245
229434098
-
AHCY
chr20
34280268
34311802
-
ABRACL
chr6
139028745
139043302
+
ADARB1
chr21
45073853
45226560
+
AL136454.1
chr1
192716132
192716653
+
ACAD10
chr12
111686056
111757107
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-let-7a-5p
chr9
94175962
94175983
+
hsa-let-7d-5p
chr9
94178841
94178862
+
hsa-let-7e-5p
chr19
51692793
51692814
+
hsa-miR-21-5p
chr17
59841273
59841294
+
hsa-miR-138-5p
chr16
56858527
56858549
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-1321
chrX
85835832
85835849
+
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-6835-3p
chr6
34240714
34240736
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC010331.1
chr19
47607873
47608454
-
AC016876.2
chr17
7581964
7584086
-
AC019205.1
chr6
73263212
73301789
+
AC020663.1
chr16
4730115
4752565
-
AC020928.2
chr19
36773712
36775908
-
AC025271.4
chr15
57553955
57555680
+
AC079781.5
chr7
97851688
97972985
-
AC104971.1
chr18
58670009
58671877
-
AC126365.1
chr17
20788071
20789584
+
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL117378.1
chr6
131901963
131920565
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.