Entry Detail


General Information

Database ID:exR0500610
RNA Name:HMGCS1
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):43287470End Site(bp):43313512
External Links:ENSG00000112972



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAAS
chr12
53307456
53324864
-
AC008575.1
chr5
112827213
112867582
+
AC010646.1
chr19
17235940
17255448
-
AC092143.1
chr16
89919165
89936092
+
AC120057.2
chr17
7240427
7244635
-
ACOT9
chrX
23701055
23766475
-
ADAR
chr1
154582057
154628013
-
ADNP
chr20
50888916
50931437
-
AEBP1
chr7
44104345
44114562
+
AGFG1
chr2
227472152
227561214
+
AHCYL2
chr7
129225023
129430211
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-let-7d-5p
chr9
94178841
94178862
+
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-199b-5p
chr9
128244783
128244805
-
hsa-miR-23b-3p
chr9
95085265
95085287
+
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-296-3p
chr20
58817626
58817647
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004847.1
chr7
44958999
44960909
-
AC016876.2
chr17
7581964
7584086
-
AC079781.5
chr7
97851688
97972985
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.