Entry Detail


General Information

Database ID:exR0500769
RNA Name:HSP90B1
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):103930107End Site(bp):103953645
External Links:ENSG00000166598



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AARS2
chr6
44298731
44313347
-
AC010422.3
chr19
12643831
12648397
-
AC099811.2
chr17
42119674
42154916
-
AC135050.2
chr16
31083439
31094956
-
AC139530.2
chr17
81703371
81720539
+
ACTG1
chr17
81509971
81523847
-
ACTG2
chr2
73892314
73919865
+
ACTR2
chr2
65227753
65271253
+
ADA2
chr22
17178790
17258235
-
ADAM23
chr2
206443532
206621127
+
ADCY6
chr12
48766194
48789037
-
AFP
chr4
73431138
73456174
+
AKR1A1
chr1
45550543
45570049
+
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3652
chr12
103930425
103930442
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC022819.1
chr15
99157231
99161140
-
AC068768.1
chr12
123262060
123262402
+
AC108134.2
chr16
3156736
3157483
-
AKT3-IT1
chr1
243793205
243794400
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.