exRNAdisease

Entry Detail

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General Information

Database ID: exR0500940 RNA Name: IGF2BP3 RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 23310209 End Site(bp): 23470491 External Links: ENSG00000136231

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA1 chr9 104781006 104928155 - AC073508.2 chr17 40627356 40665141 - AC073896.1 chr12 56285916 56316059 - AC135050.2 chr16 31083439 31094956 - AKIRIN1 chr1 38991276 39006059 + AL121594.1 chr14 35122549 35317474 + AL133352.1 chr10 100505628 100529881 - AL365205.1 chr6 41780349 41790141 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-27a-3p chr19 13836447 13836467 - hsa-miR-181a-5p chr1 198859108 198859130 - hsa-miR-181b-5p chr9 124693725 124693747 + hsa-miR-181c-5p chr19 13874725 13874746 + hsa-miR-27b-3p chr9 95085505 95085525 + hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-382-5p chr14 101054316 101054337 + hsa-miR-513a-5p chrX 147213538 147213555 - hsa-miR-320b chr1 224257049 224257070 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC021078.1 chr5 149494314 149504670 - AC133644.3 chr2 87455476 87767359 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.