Entry Detail


General Information

Database ID:exR0500944
RNA Name:IGFBP2
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):216632828End Site(bp):216664436
External Links:ENSG00000115457



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTN4
chr19
38647649
38731589
+
AC245033.1
chr15
82536788
82573194
-
AC118553.2
chr1
99970011
100083321
+
ALDOA
chr16
30064164
30070457
+
ACVR1B
chr12
51951699
51997078
+
AC093227.2
chr19
37689865
37719188
-
AC010646.1
chr19
17235940
17255448
-
AC011462.1
chr19
41350853
41425001
+
AC093525.2
chr16
2496032
2520218
+
ALCAM
chr3
105366909
105576900
+
AC093323.1
chr4
6663396
6676755
+
AHCY
chr20
34280268
34311802
-
AKAP13
chr15
85380571
85749358
+
AL358113.1
chr9
69035747
69255187
+
ACTR1A
chr10
102461881
102502712
-
ACTB
chr7
5527148
5563784
-
AC010422.3
chr19
12643831
12648397
-
AC073082.1
chr2
48632291
48755724
-
ABHD8
chr19
17292131
17310236
-
AAMP
chr2
218264123
218270257
-
AL162231.1
chr9
34664163
34666112
-
ADRM1
chr20
62302093
62308862
+
ADD2
chr2
70607618
70768225
-
ADNP
chr20
50888916
50931437
-
AGO1
chr1
35869808
35930532
+
ACTR2
chr2
65227753
65271253
+
ACAT1
chr11
108116695
108147603
+
AK1
chr9
127866486
127877675
-
ACTG1
chr17
81509971
81523847
-
ADAM19
chr5
157395534
157575775
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009022.1
chr16
69976297
70065948
-
AC009133.5
chr16
29808679
29812227
+
AC010327.5
chr19
55216660
55221616
+
AC012615.1
chr19
1874871
1876169
-
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC097478.1
chr4
89743792
89744305
+
AC106881.1
chr4
95549129
95552457
+
AC113189.2
chr17
7420103
7444081
+
AC113189.4
chr17
7439506
7445966
+
AC114284.1
chr5
120781218
120790778
+
AC132217.1
chr11
2129121
2129964
-
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.